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It inhibits the activation of the transcription factor NF-B, reducing the production of pro-inflammatory cytokines (IL-1, TNF-, IL-6) and inflammatory mediators (PGE2, NO)

GHK-Cu: An Overview of a Multifunctional Peptide. Journal of Biomaterials Science

When reintroduced through peptide therapy , GHK-Cu acts as a signaling molecule

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Effective for different genders, PT-141 has clinical data showing benefit in both men and women for sexual desire, though response patterns differ