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The evolution of dichloroacetate (DCA) as a pharmaceutical agent has a more convoluted history (202)

Abasic and oxidized abasic site reactivity in DNA: enzyme inhibition, cross-linking, and nucleosome catalyzed reactions

Operates at the nuclear protein-interaction level: Unlike metabolic or hormonal peptides that act on membrane receptors, FOXO4-DRI functions by disrupting nuclear protein interactions

Giant mitochondria in human liver disease

The peptides ability to heal gut tissues damaged by conditions such as Crohns disease and ulcerative colitis highlights its potential as a versatile therapeutic agent

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