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An experimental model aggravated by foam macrophage infiltration

Copper complexation is performed by mixing the purified tripeptide with copper(II) salts (chloride, acetate, or sulfate, depending on the protocol) at controlled pH, with the resulting complex purified by chromatography

Nanocomplexes composed of chitosan derivatives and -lactoglobulin as a carrier for anthocyanins: preparation, stability and bioavailability in vitro

Importantly, the blue complexes formed in this assay are independent of the phenolic compounds structure, ruling out coordination complex formation between metals and phenols (Singleton et al

Nature 600, 319323 (2021)

10.1021/bi00857a006 Biochemistry 49 LongoN.FrigeniM.PasqualiM