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Arginine is often evaluated in laboratory settings for its relationship to nitric-oxidelinked and amino-acid pathway biology

Efficacy of quercetin and quercetin loaded chitosan nanoparticles against cisplatin-induced renal and testicular toxicity via attenuation of oxidative stress, inflammation, and apoptosis

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doi: 10.1038/s41467-019-12873-4 31

Yet, we demonstrate that impaired Cl - extrusion underlies the failure of L838,417 to induce analgesia at high doses due to a resulting collapse in Cl - gradient, dramatically limiting the benzodiazepine therapeutic window