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It's a fascinating molecule, renowned for its targeted action on the enzyme nicotinamide N-methyltransferase (NNMT), an enzyme implicated in crucial metabolic pathways

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No adverse fetal effects have been documented from normal therapeutic doses of hydroxocobalamin in human pregnancies

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For instance, the majority (58%) of mouse microbiome studies published in 20182019 did not report the number of mice per cage, and less than 20% of studies reported using singly-housed animals 64

Mice studies suggest that inhibiting NNMT stimulates stem cells and boosts muscle repair