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[7] High-dose methionine may antagonize the therapeutic effect of L-dopa-carbidopa regimens by increasing peripheral methylation of the drug complex, potentially reducing central bioavailability

For those new to tirzepatide dosing in units , the escalation typically looks like this: 2.5mg for weeks 1-4, then 5mg for weeks 5-8, then 7.5mg for weeks 9-12, with optional increases to 10mg and 15mg for those who tolerate lower doses well but need additional appetite suppression

If given IV, it must be injected slowly (often over at least 5 minutes or diluted in a larger volume bag and infused)

Patients should expect to be a little red after the procedure, but this usually resolves in about an hour or so

There is an association with gastric antral vascular ectasia (which can be referred to as watermelon stomach), and pernicious anemia

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