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Topical licorice extract is generally considered safe during pregnancy and breastfeeding, but it's always wise to check with your healthcare provider first

This is not simply a matter of antioxidant capacity

Levy EJ, Anderson ME, Meister A

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MRPs are located in the plasma membrane of mammalian cells, while in yeast and plants they are widely located in the vacuole [76]

The reason for this is simple: The concentration of glutathione inside all cells is about a thousand times higher than outside